Eutylone and pentylone inhibited uptake at serotonin transporters (SERT), whilst dibutylone didn't. Also, eutylone and pentylone displayed weak partial releasing steps at SERT which attained 50% of maximal response. All drugs stimulated dose-relevant locomotion in mice, and eutylone was most potent and efficacious With this regard (ED50 = two mg/kg